Description
Drospirenone & Ethinyl Estradiol (YASMIN) 3 + 0.03 mg tablet is a combination of oral contraceptive or birth control pill that is used to prevent pregnancy in women of reproductive age.
Ethinylestradiol is a synthetic estrogen with similar effects to estradiol.
Drospirenone is a structural analogue of spironolactone with anti-mineralocorticoid and antiandrogenic effects, resembling the natural hormone progesterone.
Drug = Drospirenone & Ethinel Estradiol
Strength = 3+0.03mg
Contains = One month cycle
How to take
This medicine may be taken with or without food.
Try to take it at the same time each day. It must be taken regularly for it to be effective.
Take Ethinylestradiol + Drospirenone precisely as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.
Dosage of Drospirenone & Ethinyl Estradiol (YASMIN) 3 + 0.03 mg Tablet
Genital herpes, Herpes simplex infections of the skin and mucous membranes:
Contraception: Each tab contains ethinylestradiol (mg)/drospirenone (mg): 0.02/3, 0.03/3: 1 tab once daily, exactly as directed from the blister pack.
Acne vulgaris; Premenstrual dysphoric disorder: Each tab contains Ethinyl estradiol 0.02 mg/drospirenone 3 mg: 1 tab once daily, precisely as directed from the blister pack.
One tab daily for 21 consecutive days, followed by a 7-day tab-free interval.
All doses must be taken continuously at the same time each day. Refer to the detailed product guideline on how to manage missed doses and for other dosing instructions.
Missed Dose of Drospirenone & Ethinyl Estradiol (YASMIN) 3 + 0.03 mg Tablet
If you often forget to take your medicine, let your doctor and pharmacist know.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your usual dosing schedule.
Do not double a dose under any circumstances.
Overdose of Drospirenone & Ethinyl Estradiol (YASMIN) 3 + 0.03 mg Tablet
If you think you may have used Ethinylestradiol + Drospirenone more than the usual dose, please seek medical help immediately.
Signs of overdose may include the following:
- Nausea
- Vomiting
- Withdrawal bleeding
Contraindications
People with the following medical conditions should not take Ethinylestradiol + Drospirenone:
- Venous or arterial thrombotic/thromboembolic events
- Prodromi of a thrombosis
- Migraine with focal neurological symptoms
- Diabetes mellitus with vascular involvement
- Venous or arterial thrombosis
- Pancreatitis
- Hypertriglyceridemia
- Hepatic disease
- Renal insufficiency or acute renal failure
- Liver tumors
- Sex-steroid influenced malignancies
- Vaginal bleeding
- Hypersensitivity
- Pregnancy
Side Effects
Drospirenone + Ethinyl Estradiol may have the following side effects:
- Nausea
- Emotional lability
- Migraine
- Decreased/increased libido
- Depressed or altered mood
- Breast pain
- Unscheduled uterine bleeding
- Genital tract bleeding (not further specified)
Warnings
Do not take Ethinylestradiol + Drospirenone with the following medicines:
- Phenytoin
- Barbiturates
- Primidone
- Carbamazepine
- Rifampicin
- Oxcarbazepine
- Topiramate
- Felbamate
- Ritonavir
- Griseofulvin
- St. John’s wort
- Cyclosporin
- Lamotrigine
- Angiotensin-II-receptor antagonists
- K-sparing diuretics
- Aldosterone antagonists)
- HIV/HCV protease inhibitors
- Drospirenone
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicine, supplements, and medicines that you buy without a prescription.
This list does not include all medicines that may interact with Ethinylestradiol + Drospirenone may not be suitable.
How Does It Work?
Ethinylestradiol and drospirenone work by suppressing ovulation by negative feedback mechanism on the hypothalamus, which changes the secretion of normal gonadotropin pattern of Follicle Stimulating Hormone and Luteinizing Hormone by the anterior pituitary gland, thereby blocking the follicular FSH phase and the midcycle surge of gonadotropins. The changes in cervical mucus and the endometrium leads to the inhibition of sperm penetration and unfavorable environment for nidation, respectively.
Uses
Drospirenone + Ethinyl Estradiol is used to treat the following conditions:
- Contraception
- Acne vulgaris
- Seborrhea
- Premenstrual dysphoric disorder
- For women who experience hormone-related fluid retention and the resulting symptoms
Special Precautions and Connected Warnings
Take special precautions if you have the following conditions:
- Circulatory disorders
- Tumors
- Renal insufficiency
- Hypertriglyceridemia
- Hypertension
- Jaundice or pruritus related to cholestasis
- Gallstone formation
- Porphyria
- Systemic Lupus Erythematosus
- Hemolytic uremic syndrome
- Sydenham’s chorea
- Herpes gestationis
- Otosclerosis-related hearing loss
- Diabetes
- Crohn’s disease
- Ulcerative colitis
- Chloasma
- Avoid alcohol and grapefruit juice.
Storage Conditions
- Store below 25°C.
- Store in a cool, dry place away from the reach of children.
- Do not use Drospirenone + Ethinyl Estradiol that is expired or out of date.
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