Tretinoin (RETINO-A Cream) 0.05% w/v Cream 1 tube

Original price was: $10.37.Current price is: $9.60.

Tretinoin is a form of vitamin A used to treat acne, which appears as spots or pimples and helps to smooth rough facial skin and reduce fine wrinkles on the skin. It is also used to treat acute promyelocytic leukemia, a type of blood problem that slows certain types of diseased blood cells. Each cream contains 0.05% w/v of Tretinoin as its active ingredient.

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Tretinoin is derived from vitamin A that has found its importance in the field of dermatology. It is used to treat all types of acne from dark spots to pimples on the face and other parts of the body. It also helps to smoothen rough skin and reduces the age related wrinkles and lines. Each cream contains 0.05% w/v of Isotretinoin as its active ingredient.

Drug = Tretinoin

Strength = 0.05% w/v

Contains = 1 tube

How to use

Tretinoin comes as a gel, foam, and a cream to apply to the skin.

It is usually applied twice a day, in the morning and the evening. 

To help you remember to use Tretinoin, use it at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. 

Use Tretinoin precisely as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Recommended dose of Tretinoin (RETINO-A Cream) 0.05% w/v Cream

Uneven skin tone, fine lines and wrinkles or damage brought about by exposure to UV rays :

 Adult: 0.02 or 0.05% cream preparation: Apply a pea-sized amount on clean fingers and spread evenly on the face and neck at night. Results can be seen in 6 months 

Acne vulgaris: 

Adult: 0.01-0.1% cream or gel preparation: Apply once or twice daily on the face after cleansing. Results may be seen in 4-6 weeks.

Missed Dose of Tretinoin (RETINO-A Cream) 0.05% w/v Cream

Just apply the missed dose and then continue with the regular dosing schedule. 

Do not double the dose under any circumstances.

Overdose of Tretinoin (RETINO-A Cream) 0.05% w/v Cream

Frequent application of Tretinoin more than the prescribed dose can lead to severe redness of the area of application. If this happens, seek help immediately.


People with the following medical conditions should not take Tretinoin:

  • Pregnancy (first trimester)
  • Lactation

Side Effects

Tretinoin may have the following side effects:

  • Skin irritation
  • Stinging
  • Warmth
  • Erythema
  • Dryness
  • Pruritus
  • Peeling
  • Blistering
  • Crusting
  • Discomfort
  • Temporary hypopigmentation and hyperpigmentation (rare)
  • Edema
  • Atrophy
  • Photosensitivity


Do not take Tretinoin with the following medicines:

  • Headache
  • Nausea
  • Vomiting
  • Mucocutaneous symptoms
  • Transient headache
  • Facial flushing
  • Cheilosis
  • Abdominal pain
  • Dizziness
  • Ataxia

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicine, supplements, and medicines that you buy without a prescription.

This list does not include all medicines that may interact with Tretinoin.

How Does It Work?

Tretinoin works by decreasing the cohesiveness of follicular epithelial cells by stimulating mitosis and turnover. It causes the extrusion of existing comedones and prevents the formation of new ones. It has a thinning effect on the stratum corneum and can modify abnormal follicular keratinization. 


Tretinoin is used to treat the following conditions:

  • Mottled hyperpigmentation
  • Roughness and fine wrinkling of photodamaged skin
  • Acne vulgaris

Special Precautions and Connected Warnings

Take special precautions if you have the following conditions:

  • Eczema
  • Sunburn
  • History of skin cancer
  • Depilation
  • Chemical hair treatment and peels
  • Dermabrasion or laser resurfacing
  • Renal or hepatic impairment
  • Children
  • Pregnancy

Storage Conditions

  • Store between 15-30°C and protected from light.
  • Store in a cool, dry place away from the reach of children.
  • Do not use Tretinoin that is expired or out of date.


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